ABSTRACT

Our group has explored the use of LTCC substrates to construct a microchip CE system utilizing a 25-µm wire for EC detection [51]. The LTCC substrates are relatively inexpensive to fabricate and are similar to glass in their electroosmotic properties. The ceramics are opaque, but they do not need to be transparent for electrochemical detection. The electroosmotic flow of the ceramic chips was found to be similar to that of silica. Separation of catechol and dopamine was accomplished in about 45 s.