Figure 11 Time-dependent frequency changes resulting upon the biocatalyzed precipitation of (8) onto an Au-quartz crystal modified with the (13)-oligonucleotide sensing monolayer, which was interacted with the target DNA, (14), 5.8×10

Figure 11 Time-dependent frequency changes resulting upon the biocatalyzed precipitation of (8) onto an Au-quartz crystal modified with the (13)-oligonucleotide sensing monolayer, which was interacted with the target DNA, (14), 5.8×10−7 mg·mL−1 that was pre-hybridized with the biotinylated oligonucleotide, (15), 2.6×10−6 mg·mL−1. The resulting tricomponent ds-assembly on the Auquartz crystal was then reacted with the avidin-HRP conjugate, (16). Curve (a) shows the frequency changes upon the precipitation of (8) in the presence of (7), 5×10−3 M, and H2O2, 5×10−3 M. Curve (b) shows the frequency in the similar experiment where the sensing interface was interacted with the normal gene (14a) pre-hybridized with (15) and interacted with avidin-HRP, (16).