Figure 24 Chronocoulometric transients for (a) A bare Au-electrode. (b) The oligonucleotide (33)-modified Au-electrode. (c) The (33)-modified Au-electrode after hybridization with M13φ, 2.3×10 M, for 1.5 hours. (d)

doi:10.1201/9780203908907-40

Chapter

Figure 24 Chronocoulometric transients for (a) A bare Au-electrode. (b) The oligonucleotide (33)-modified Au-electrode. (c) The (33)-modified Au-electrode after hybridization with M13φ, 2.3×10 M, for 1.5 hours. (d)

Chapter

ABSTRACT

A similar approach [48] was used for the amplified sensing of the 11161 base RNA of vesicular stomatitis virus (VSV) [49], using reverse transcriptase (enhanced avian reverse transcriptase) as the replication biocatalyst. The oligonucleotide, (35), was immobilized as the primer sensing interface on an Au-elec-trode or an Au-quartz crystal, 1.4×10−11