ABSTRACT
The k 01 for pure catalase from human erythrocytes is 3:4 107 M1 sec1. This value permits estimation of the concentration of catalase in blood and tissues.
There are some problems in estimating the concentration of catalase because of molecular heterogeneity due to genetic origin (not all isozymes have the same specificity), conformational alterations due to -SH group oxidation or dissociation of the active tetramer (catalatic activity) into the dimer which has peroxidatic activity but not catalatic activity (6-8).
