Table 2 A Simplified Short Wide Table Test 1 Test 2 Test 3 Test 4 Test 5 Test 6 Test 7 Test 8 Test 9 SLA-0017 95 39 68 48 2 62 12 22 24 SLA-0012 91 54 24 99 5 54 66 27 SLA-0011 90 37 4 32  68 71 50 73 SLA-0022 89 37 58 23 28  38 92 52 SLA-0001 87 73 87 0 71 25 23 45 0 SLA-0004 81 63 76 42 95 12 94 31 39 SLA-0008 78 52 61 25 32 99 73 95 61 SLA-0013 78 51 37 84 25 39 38 71 100 SLA-0019 74 2 2 80 43 23 99 99 100 SLA-0010 62 4 37 76 5 46 85 55 52 SLA-0009 51 43 59 68 1 71 10 3 65 SLA-0002 49 62 38 66 3 73 30 21 64 SLA-0021 35 66 40 80 63 88 28 54 82 SLA-0003 35 92 76 17 58 23 18 84 76 SLA-0006 25 38 55 17 90 2 99 11 78 SLA-0005 22 35 22 13 87 42 34 61 48 SLA-0015 20 82 4 31 63 39 66 46 93 SLA-0018 16 22 79 3 97 7 91 91 68 SLA-0014 15 86 86 4 62 85 100 95 89 SLA-0023 11 55 18 42 95 91 33 95 24 SLA-0007 11 14 26 90 83 97 92 58 100 SLA-0020 10 18 67 77 52 15 64 50 8 SLA-0016 5 42 22 7 1 91 69 48 92

doi:10.1201/9780203910696-100

Chapter

Table 2 A Simplified Short Wide Table Test 1 Test 2 Test 3 Test 4 Test 5 Test 6 Test 7 Test 8 Test 9 SLA-0017 95 39 68 48 2 62 12 22 24 SLA-0012 91 54 24 99 5 54 66 27 SLA-0011 90 37 4 32 68 71 50 73 SLA-0022 89 37 58 23 28 38 92 52 SLA-0001 87 73 87 0 71 25 23 45 0 SLA-0004 81 63 76 42 95 12 94 31 39 SLA-0008 78 52 61 25 32 99 73 95 61 SLA-0013 78 51 37 84 25 39 38 71 100 SLA-0019 74 2 2 80 43 23 99 99 100 SLA-0010 62 4 37 76 5 46 85 55 52 SLA-0009 51 43 59 68 1 71 10 3 65 SLA-0002 49 62 38 66 3 73 30 21 64 SLA-0021 35 66 40 80 63 88 28 54 82 SLA-0003 35 92 76 17 58 23 18 84 76 SLA-0006 25 38 55 17 90 2 99 11 78 SLA-0005 22 35 22 13 87 42 34 61 48 SLA-0015 20 82 4 31 63 39 66 46 93 SLA-0018 16 22 79 3 97 7 91 91 68 SLA-0014 15 86 86 4 62 85 100 95 89 SLA-0023 11 55 18 42 95 91 33 95 24 SLA-0007 11 14 26 90 83 97 92 58 100 SLA-0020 10 18 67 77 52 15 64 50 8 SLA-0016 5 42 22 7 1 91 69 48 92

Chapter

Table 2 A Simplified Short Wide Table Test 1 Test 2 Test 3 Test 4 Test 5 Test 6 Test 7 Test 8 Test 9 SLA-0017 95 39 68 48 2 62 12 22 24 SLA-0012 91 54 24 99 5 54 66 27 SLA-0011 90 37 4 32 68 71 50 73 SLA-0022 89 37 58 23 28 38 92 52 SLA-0001 87 73 87 0 71 25 23 45 0 SLA-0004 81 63 76 42 95 12 94 31 39 SLA-0008 78 52 61 25 32 99 73 95 61 SLA-0013 78 51 37 84 25 39 38 71 100 SLA-0019 74 2 2 80 43 23 99 99 100 SLA-0010 62 4 37 76 5 46 85 55 52 SLA-0009 51 43 59 68 1 71 10 3 65 SLA-0002 49 62 38 66 3 73 30 21 64 SLA-0021 35 66 40 80 63 88 28 54 82 SLA-0003 35 92 76 17 58 23 18 84 76 SLA-0006 25 38 55 17 90 2 99 11 78 SLA-0005 22 35 22 13 87 42 34 61 48 SLA-0015 20 82 4 31 63 39 66 46 93 SLA-0018 16 22 79 3 97 7 91 91 68 SLA-0014 15 86 86 4 62 85 100 95 89 SLA-0023 11 55 18 42 95 91 33 95 24 SLA-0007 11 14 26 90 83 97 92 58 100 SLA-0020 10 18 67 77 52 15 64 50 8 SLA-0016 5 42 22 7 1 91 69 48 92

ABSTRACT

One of the goals of pharmaceutical research has been to find the relationship between small-molecule chemical structure and biological activity. One simple, but widely used, method of analysis is the structure-activity relation report. This report shows a chemical structure and pieces of information describing the activity on each row. An example of a structure-activity report is shown in figure 7. The addition of quantitative measures of physicochemical properties is called QSAR and is the province of molecular modelers. Structure-activity relationship reports