ABSTRACT
Numerous advances in solid-phase synthesis methodologies have been published in the literature in the past decade. In fact, most solution-phase synthetic transfer-mations have now been performed in some form on solid supports. This section presents brief descriptions of many of the most recent solid-phase synthesis advances and attempts to explain the importance of these methods for the rapid synthesis of compound libraries. The reader can expect to gain from this section a good overview of the current state of the art and where the field of solid-phase synthesis is headed at the beginning of the 21st century.
