ABSTRACT
Data management is an integral requirement of any high-throughput screening (HTS) effort. Ultimately, the purpose of any screening program is to acquire information that can be turned into knowledge in the drug discovery process. In order to achieve this goal, the results of all tests, along with all appropriate contextual information, must be reliably captured by a data management system and made available to researchers throughout an organization. The tracking of sample locations, test conditions, the capture of raw results, and the transformation of raw results into calculated and meaningful information requires robust and flexible information systems with effective user interfaces, as well as links to inventory and other information systems. This chapter will highlight some of the issues involved in developing and maintaining an informatics system to support HTS.
