ABSTRACT

Caenorhabditis elegans is a small nematode worm containing somewhat less than 1000 postmitotic, somatic cells at adulthood. Its invariant, mosaic pattern of development and self-fertilizing hermaphroditic life style have made it favorite of developmental biologists second only to Drosophila. Details on numerous aspects of its development and other aspects of current studies have been compiled in two books (1,2), and detailed methodologies can be found in the journal Methods in Cell Biology, Vol. 48 (3). Several online sources of information are available, including an informal newsletter, published by the C. elegans Stock Center (https://elegans.swmed.edu/), which also includes access to all nematode publications (4654 at the time of this writing, including 146 cross referenced to aging). Numerous bioinformatics resources are available and can be accessed through the same URL or at https://www.wormbase.org/ and other sites.