ABSTRACT
The study of pharmacokinetic processes-absorption, distribution, and elimination-is fundamental to determining the appropriate dosing regimen for an individual patient administered a drug by systemic routes. Pharmacokinetics has also been indispensable in designing an improved therapeutic agent or the means by which it is delivered. Quite often, pharmacokinetic analyses of systemically useful drugs is approached by dividing the body into a series of compartments that mathematically represent tissue levels of drug over time as a summation of exponentials. The number of compartments that are chosen are equal to and limited by the number of exponentials that can be assigned to the concentration of drug found in a particular body tissue and/or fluid over time.
