ABSTRACT

In this chapter we describe recent advances in the use of quartz crystal microbalance (QCM) frequency shift and quartz crystal admittance/ impedance analysis of selfassembled protein films complemented by ellipsometric thickness, and comparison of acoustic and optical mass/thickness. These protein films can be regarded as model systems among other applications of electrochemical biosensors based on molecular recognition and electrical signal generation through electrocatalysis of “wired” (electrically connected) enzyme electrodes.