ABSTRACT
Design and manufacture of drug carrier systems has been a challenging area of research over the last 30 years which has led to a choice of suitable colloidal systems, including liposomes [1-3], nanoparticles [4-11], and block copolymer micelles [12, 13]. The main advantage of using such colloidal systems is given by their submicronic size, allowing them to be administered intravenously without any risk of embolization and promoting their diffusion through capillary vessels [14] and even through mucosae [15]. This particle size range is also desirable for subcutaneous and intramuscular administration [16] and offers new functions such as large specific surface areas, considerable surface properties, improved solubility, and adhesion to tissues [17].
