ABSTRACT

Transarterial lung perfusion scintigraphy (TLPS) is a nuclear medicine test that is able to quantify an arteriovenous (AV) shunt in the limbs. It is based on the injection of TC-99m labeled macroaggregated albumin first in the vein and then in the artery and on scanning of radiotracer on the lungs in order to quantify the tracer that has passed the shunt and gets trapped in the lung. A two-step curve is obtained, one after venous injection and a second after intra-arterial injection, which is able to quantify the shunt. The test is effective for postprocedure appraisal and for assessment of the natural course of the anomaly.