ABSTRACT

Lymphatic leakage is a common complication of lymphangioma circumscriptum (LC). The therapeutic interventions for LC are difficult and frustrating because of the high recurrence rate due to multifocal lesions and a failure to address the deeper component of a lesion. The various modalities that have been used to manage LC are surgical excision, sclerotherapy, electrocautery, radiofrequency, radiotherapy, carbon dioxide laser, imiquimod 5% cream, pulsed-dye laser, electrocoagulation, therapeutic lymphangiography, and sirolimus. Sirolimus was recently reported to treat lymphatic leakage in LC and showed remarkable results. It is a very promising first line of treatment for LC.