ABSTRACT
Infection........................................................... 405 20.8 NSAIDS ............................................................................................. 406 20.9 Occupation ....................................................................................... 407 20.10 Pesticides .......................................................................................... 407 20.11 Pancreatic Pathways — Molecular Epidemiology and the Study
of Gene-Environment Interactions.................................................. 409 20.11.1 Carcinogen Metabolism, Oxidative Stress......................... 409
20.11.2 Inflammation ....................................................................... 410 20.11.3 DNA Repair ......................................................................... 411 20.11.4 Hormonal Pathways ........................................................... 412
20.12 Epilogue............................................................................................ 413 References .................................................................................................. 414
Adenocarcinoma of the exocrine pancreas has the lowest 5-year survival (<4%) of all cancers and is the fourth leading cause of cancer-related deaths in men and women in the United States.
