ABSTRACT

Differentiation ....................................................... 12 1.3.2 Epithelial-Mesenchymal Signaling........................................ 13 1.3.3 The Lineage of Endocrine Cell Types ................................ 15

1.4 Pancreatic Organogenesis in Nonmammalian Models.................... 16 1.4.1 Pancreatic Development in the Zebrafish

(

Danio rerio

, Formerly

Brachydanio rerio

) ....................... 17 1.4.2 Pancreatic Development in

Xenopus laevis

........................ 22 1.4.3 Pancreatic Development in the Chick ................................ 25

1.5 Pancreas Embryology in Humans .................................................... 26 1.5.1 Pancreatic Development and Human Disease................... 27

1.6 Epilogue..............................................................................................27 References ....................................................................................................28