ABSTRACT

There are many indications for the administration of neuromuscular blocking agents in the paediatric intensive care unit (PICU) and these are summarised in Table 1. The most common indications are to facilitate endotracheal intubation and to prevent patient-ventilator dyssynchrony, particularly during “unphysio-logical” techniques such as high frequency oscillatory ventilation, inverse ratio ventilation or controlled hypoventilation. Other indications centre around the management of specific clinical conditions.