ABSTRACT
All children with type one diabetes mellitus (T1DM) require insulin replacement therapy in order to normalise blood glucose concentrations and minimise the risk of the long-term complications of diabetes. Insulin is almost invariably administered via subcutaneous injection, either as a combination of long- and short-acting insulin preparations in a 2-, 3- or 4-injection per day regime, or by the continuous infusion of short-acting insulin via a pump [1].
