ABSTRACT
Studies in humans are indispensable for assessing and evaluating risks following the intake of food. The screening of substances for toxicity can be carried out in experimental animals. Extrapolation of the results to humans, however, is difficult. In laboratory 196experiments, the animals are locked up and the investigator regulates the exposure conditions (usually exposure to a single substance). In addition, the genetic background of experimental animals is often the same, as inbred strains are used. Except for the exposure, most conditions are maintained constant.
