ABSTRACT
This chapter studies the role of extrapolation in the risk assessment of chemicals occurring in food. The concept of extrapolation is briefly introduced in Section 18.2. Both inter- and intraspecies (interindividual) extrapolation of data on chemicals showing a threshold in their dose—response relationship, and high-to-low dose extrapolation of chemicals which do not, are discussed. Further, some problems, which are in a certain sense specific to food chemicals, are presented.
