ABSTRACT
The fever originates from the inflammatory process and fat necrosis, accompanying acute pancreatitis of any cause. Additional symptoms and signs of pancreatitis, such as pain and “surgical abdomen” prevail. Gaucher’s Disease is the most common, inherited metabolic disorder of glycolipid metabolism. The clinical course is characterized by recurrent transient attacks of fever, severe constitutional symptons associated with amyloidosis, nephropathy, and hyperglobulinemia. Thus, it resembles closely familial mediterranean fever with deafness. Hypernatremic dehydration may be associated with high fever, in addition to other major clinical manifestations. Its main etiology being diabetes insipidus of either pituitary or nephrogenic origin. Hypernatremic dehydration should be considered in the differential diagnosis of patients presenting with fever and impaired cerebral function.
