ABSTRACT
This chapter focuses on developments made with the simulated moving bed, with particular emphasis on Aston University semicontinuous chromatographic refiner (SCCR) systems and their applications in liquid separations. The various SCCR systems used for dextran fractionation were packed with Spherosil XOB075 of 200- to 400-μm porous silica beads, employing the slurry packing technique. The SCCR7 Mkl system was used in the anion-exchange mode to investigate factors affecting the separation of synthetic equimolar glucose-fructose and hydrolyzed sucrose feedstocks. The great separation potential and versatility of chromatography have been widely accepted and has been established as a powerful analytical tool. In moving-bed systems the stationary phase flows under gravity countercurrent to a stream of mobile phase flowing upward. The moving-column continuous systems consist of a circular array of interconnected columns, which rotate as a whole past fixed inlet and outlet ports.
