ABSTRACT
This chapter focuses on the developments in the modeling of semicontinuous countercurrent chromatographic refiners (SCCRs), which employ the moving-port principle to achieve the countercurrent movement between the stationary and mobile phases. The computer program is easily adaptable to account for different system dimensions, number of columns, and separation efficiency and can therefore be applied to other SCCR systems used in carbohydrate separations. In 1973, A. B. Sunal developed a simulation program for gas-liquid chromatography based on plate-to-plate calculations to describe the operation of circular coun-tercurrent chromatographic equipment. The program is rearranged to account for up to three components: the retarded fructose due to calcium ion complexing, the lesser retarded glucose, and the faster-moving impurities. The program can, however, be modified easily to predict the on-column concentration profiles instead. In the work the on-column concentration profiles are predicted instead of the purge profiles.
