ABSTRACT
Several techniques have been proposed for continuous chromatographic systems in preparative separations. The rotating annular chromatograph in which adsorbents are packed in an annulus is one of the two-dimensional separation processes. A series of papers show the ability of the rotating annular chromatograph to separate metal ions in solution. A continuous rotating annular chromatograph (CRAC) consists of a stationary annular bed and rotating feed nozzles and product collectors. The concept of the separation of a multicomponent mixture is the same as a CRAC with isocratic elution. The CRAC has been shown to operate effectively as a preparative chromatograph. The feed can be supplied to the system continuously and the products can also be collected continuously. The mathematical description of CRAC is similar to that for conventional column chromatography. CRAC with stationary bed and rotating nozzles and product collectors has several advantages over the rotating bed systems: cost reductions due to lower requirements for rotating power and better scale-up potential.
