ABSTRACT
The search for tools to monitor disease activity in multiple sclerosis (MS) has expanded in recent years. Availability of new therapies has prompted reassessment of clinical examination scales and development of new magnetic resonance imaging (MRI) techniques to improve trial efficiency such that effective therapies are promptly recognized. This chapter will review the use of standardized examination scales, MRI, cerebrospinal fluid (CSF) and evoked potentials (EP) for monitoring disease activity in MS.
