ABSTRACT
Metastatic breast cancer is a grave condition and a heterogeneous disease that has a variety of different clinical scenarios, ranging from solitary metastatic lesions to diffuse and multiple organ involvement and is the main cause of breast cancer–related death. This chapter elaborates on the epidemiology, pathophysiology, clinical features, and management of metastatic breast cancer. The management of metastatic breast cancer involves a systemic approach along with local therapies for symptom control. In spite of treatment, survival of metastatic breast cancer is not very good. Several newer molecules are under trial with modern systemic therapies.
