Soil affects human health positively and negatively, directly and indirectly. In the Anthropocene, human activities can also improve or degrade soil health depending on the specific land use and soil management. Soil can positively impact human health by providing nourishment, medicaments, or antibiotics, and through environmental quality in relation to air breathe and water drink. Climate change may have adverse impacts on soil health and thus on nutritional quality of the food produced from soil. Therefore, directly, soil affects human growth through quantity and quality of food produced and the nutrition provided through. Thus, use of micronutrient-enriched organic by-products can be used as soil amendments to improve soil health and nutritional value of food products. Therefore, urgency to improve soil health to mitigate human malnutrition has increased interest about the impact of land use and management on a soil health.