ABSTRACT

Mycotic Keratitis (MK) is also known as fungal keratitis and is considered as one of the major causes of corneal blindness, especially in tropical and subtropical environments. Qingdao in Northern China reported 654 MK patients from January 1999 to December 2004. Although, various approaches such as pharmacological treatment, surgery and corneal crosslinking are investigated for the management of MK, unfortunately none of these approaches are very effective in the management for MK. MK is sometimes followed by an autoimmune condition known as Sympathetic Ophthalmia, which is a result of retinal antigen reaction to conjunctival or orbital lymphatics. The responsiveness of an individual to the treatment of MK is also monitored by in vivo confocal microscopy and anterior segment optical coherence tomography. It is proposed that the ideal and effective antifungal drug used in the treatment of MK should not be irritating and toxic for the eyes.