ABSTRACT
Fungal Keratitis (FK) is a serious blinding eye disease. Delayed or inappropriate treatment may result in eye enucleation. In endogenous fungal keratitis, the concealed pathogenesis is easy to cause a misdiagnosis, resulting in delayed treatment. Severe fungal corneal ulcer is often accompanied by hypopyon and inflammation in the anterior segment. For patients with corneal inflammation, which could not be controlled by local and systemic antifungal therapy, and lesions, which tend to enlarge or perforate, keratoplasty is the only way to control infection and save useful vision. Fungal recurrence after corneal transplantation is a serious surgical complication for FK patients. The chapter summarizes some special cases and difficult problems the authors have encountered in the clinical diagnosis and treatment of FK. Endogenous fungal infection should be considered while treating deep fungal infection with a clinical history of trauma.
