ABSTRACT
Which of the following is CORRECT regarding the nephron?
The glomerulus is about 20 μm in diameter and is formed by the invagination of a tuft of capillaries into the dilated, open end of the nephron (Bowman’s capsule).
Functionally, the glomerular basement membrane permits the free passage of neutral substances upto 4 nm in diameter and totally excludes those with diameters greater than 8 nm.
In the distal convoluted tubule, while the predominant principle cells (P) are involved in acid secretion and HCO3 − transport, the intercalated cells (I) are associated with Na+ reabsorption and vasopressin-stimulated water reabsorption.
The renin-secreting juxtaglomerular cells are situated in that part of the thick ascending limb of the loop of Henle, which traverses close to the afferent arteriole from which the tubule arose.
In a resting adult, the kidneys receive about 450 mL of blood per minute.
