ABSTRACT
Alginate (ALG) is a preferred biodegradable biomaterial which consists of β-D-mannuronic (M) and α-L-guluronic acid residues used in bionanocomposite formulation, especially in biomedicines such as cell transplantation, regeneration of skin, cartilage, bone, liver, cardiac tissue, wound dressings, and scaffold materials. Bionanocomposites can be considered as the new emerging group of nanostructured hybrid materials. The results suggested that the ALG/silver nanoparticle bionanocomposites might have the potential for application as wound-dressing materials. These properties of ALG fiber prompt a lot of potential applications in the different fields, for example, in medicinal chemistry as delivery vehicles for drugs and cells, for enzyme entrapment; in the environmental applications as heavy ion scavengers and as adsorption of dye materials. Graphene oxide is one of the most popular carbon materials. The antibacterial activity of the Ag/ALG/nicotinamide wound-dressing material was evaluated against E. coli and S. aureus. The wound healing and histological studies were evaluated using burn diabetic rat animals.
