ABSTRACT
Cells which we deliver to regenerate the tissues can also work as cross-linkers for the formation of alginate (ALG) hydrogels. The complications associated with specified techniques are circumvented by a new paradigm called "tissue engineering" (TE). As the name suggests, tissue engineering is the application of engineering methodologies in life sciences for developing functional tissues in vitro, which are then easily transplanted in vivo. Delivery of drug and growthfactors is essential in the maintenance of tissue homeostasis and internal regularization. The interaction between biopolymer and bioactive bioceramic lead to the regeneration of damaged skin tissue. Bone TE deals with methods and practices involved in fabrication of constructs that resemble the physical, chemical, and biological properties of natural bone tissue. E. V. Solovieva et al. designed a series of freeze-dried ALG–fibrinogen composite scaffolds for engineering of skin tissues severely damaged by burns and trauma.
