ABSTRACT
Cannabis was an accepted medicine during the second half of the 19th century but its use was declined as single agent pain medications were advocated by physicians who demanded standardization of medicines. Numerous therapeutic effects of cannabis have been reviewed but cannabis-based medicines are still an enigma because of legal issues. The chemical compounds (phytocannabinoids) in cannabis bind and interact with the naive endocannabinoids in the human body that triggers cannabinoid receptors to achieve homeostasis in the body to stop disease. Cannabis phytocannabinoids can provide the antioxidant benefits needed to inhibit oxidation. Several lab studies support cannabis constituent cannabidiol as an antioxidant and neuroprotectant, but clinical studies are needed to research which cannabinoids, terpenes, and flavonoids are most effective against numerous disorders. The phytocannabinoids in cannabis can provide antioxidant and anti-inflammatory activity for neuronal protection. Cannabis cannabinoids may slow down the buildup of amyloid plaques and tangles or reduce the inflammatory process leading to their buildup.
