ABSTRACT

This chapter seeks to identify the medicinal-plant extracts involved in the biosynthesis of Au- and Ag- nanoparticles (NP). In addition, the characterization and identification of particle morphology was undertaken with a view to update the nanobiotechnology of NPs and their anticancer activities. Ag-NPs fabricated from various medical plants have also shown anticancer properties due to structurally diverse chemical constituents present in them. A clear understanding of the interactions of Au- and Ag-NPs with the cancerous cell is vital for the assessment of anticancer activity and for further advanced biomedical applications. Cancer is recognized as a dangerous disease. It is characterized by various signaling mechanisms, for instance, cell proliferation, angiogenesis, and metastasis. Both Au- and Ag-NPs have shown cytotoxic efficiency against various types of cancerous cells. Studies have confirmed that cancer cell growth has been significantly decreased in a concentration-dependent manner after treatment with biogenic fabricated gold and silver nanoparticles.