ABSTRACT

The revolution that started in the year 1999 in the field of network theory has changed drastically the mathematical and computational approaches to biology. It was realized that networks within the living things - protein, metabolic, gene regulatory, neural, etc. networks - obey the same laws with all other dynamic evolutionary networks, from space-time ones to electronic, social, ecological and financial networks, and even the World Wide Web. Networks became the mainstream research area in bioinformatics and computational postgenomic biology, with hundreds of publications devoted to their characterization, and relation to biological function. The next 10-15 years are expected to be the most exciting in the history of biology and medicine, promising to redefine major biological functions and disease mechanisms in terms of biological networks and pathways. The symposium will focus on the mathematical and computational aspects of bionetworks topology and dynamics and structure-function relationships.