ABSTRACT
Metal–peptide frameworks (MPFs) are a new class of materials based on the coordination of a metal ion and a peptide, a peptide mimetic, or a protein. They are inspired by the vast number of structures that have been reported for metal–organic frameworks and by the virtually unlimited potential of (short, typically 2–4 amino acids long) peptides to form intricate self‐assembled and chiral crystals. The potential of MPFs extends far beyond biological applications, although of course, they are in part inspired by natural, peptide‐based structures. Using well‐defined, monodisperse (oligo)peptides, the construction of (functional) materials based on metal‐controlled peptide self‐assembly has become feasible and numerous fields such as materials for drug delivery, catalytically active chiral porous solids, or sensors have been suggested to benefit from the advanced MPFs reported in the literature. MPFs also constitute a grand challenge for reticular chemistry as far as the rational design is concerned. This entry summarizes the state of the art in MPF research.
