ABSTRACT
Synthesis of chiral compounds that are di‚cult to obtain by thermochemical reactions but readily accessible by photochemical reactions is certainly one of the major motivations for promoting the study on photochirogenesis. e photochemical routes to chiral compounds are particularly e‚cient or even essential for the construction of such compounds that are thermally unstable, highly constrained, and/or polycyclic. e switching of chemo-and stereoselectivity, o…en observed upon photoexcitation as a consequence of the promotion of an electron to the antibonding orbital and the subsequent alterations in reactivity and redox properties, renders the photochirogenic route an attractive alternative to the conventional catalytic and enzymatic counterparts. Indeed, the photochirogenesis has now become an indispensable and practical protocol for synthesizing molecules of complex structures, such as naturally occurring and bioactive complex organic compounds.2
