ABSTRACT

Photosensitizing e¨ects of xenobiotics are of increasing concern in dermatology since modern lifestyle o«en associates sunlight exposure with the presence of chemical substances in the skin. Photosensitization is defined by the development of abnormal cutaneous reactions triggered by sunlightdosesregardedasharmless,mosto«enintheUVArange(320-400nm).§ephotosensitizing compound, generally not toxic by itself, becomes reactive under irradiation. An important number of chemicals like perfumes, sunscreen components, or therapeutic agents have been reported as photosensitizers [1-5].