ABSTRACT

This chapter describes some of the system integration solutions for optics and detection as well as the possibilities for integration of sample preparation and processing components. Robust, portable microflow cytometers to be used at the point-of-care and in the field must be designed and developed with the integration of many miniaturized components. Microphotonics strives to integrate the required optical devices on a single chip, and focuses on device size, functionality, and fabrication technology. The chapter provides examples of optical components, based on microphotonics or optofluidics, which could be included in microflow cytometers to make them smaller, cheaper, or more robust, or to impart functionalities. Beyond integration of system components for miniaturization and sample preparation, processing after analysis will lead to new and exciting opportunities to create systems of advanced function. Developers of microflow cytometers constantly address the challenges of shrinking feature sizes while adding new functions.