ABSTRACT

Control of microorganisms within a manufacturing facility is a critical quality parameter of cosmetic/personal care products industry. These products is not expected or required to be sterile, but the presence of excessive numbers of microorganisms or pathogenic/objectionable microorganisms is not acceptable. Good manufacturing practices (GMPs) are typically established to put in place controls that prevent microbial contamination during manufacturing. In order to confirm microbiological control, microbial monitoring is performed on critical portions of a manufacturing facility including environmental air, equipment and facility surfaces, and manufacturing systems.