ABSTRACT

Classical biomolecule identification usually involves separation of a complex mixture followed by analysis of the separated fraction. No single test provides the definitive identification of an unknown biomolecule; hence a complex series of tests are required. This process is often time-consuming and not available on the time scale desired in clinical laboratories. These factors and the need to be able to adapt to primitive field test conditions have prompted many researchers to explore modern instrumental alternatives to classical procedures. The characteristics of most modern analytical tools include rapid data acquisition, reproducibility, computer-aided instrument control, and data analysis. A number of modern instrumental techniques have also been adapted for field applications.