ABSTRACT
This chapter details the gross and histologic manifestations of depositional diseases in reptiles and, when possible, provide information regarding the underlying pathophysiologic mechanisms and clinical sequelae. Depositional diseases, defined as the abnormal intra- and/or extracellular accumulation of various organic and inorganic compounds within the parenchyma or potential spaces of tissues and body cavities, can be a common finding in captive, and to a lesser degree, free-ranging reptiles. Uric acid is produced as a byproduct of protein and nucleotide metabolism and excreted by the renal tubules. Excessive concentrations of uric acid in the body therefore occur with increased production or decreased excretion. Gout has been reported in all types of reptiles, namely snakes, lizards, terrestrial chelonians (tortoises), and crocodilians. One of the most important organs for the interpretation of lipid deposits is the reptilian liver.
