ABSTRACT

Animal models provide important knowledge of pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals. Generally speaking, securing animals of a particular species, strain, type, or age is very important in the selection of experiment animals. In some developed countries such as the United States, the availability of commonly used animals in orthopaedic research is not a problem. Financial limitations such as the size of the grant or the definite amount of money available for the project are important factors in selection of animals. The existing research data in the literature for an animal species, such as anatomy, physiological features, or the responses to drugs and surgical procedures, especially the information relevant to orthopaedic research, are very important for the selection of research animals. The rabbit is one of the most commonly used animals in orthopaedic research. This chapter lists the suggested animal models for common orthopaedic studies.