ABSTRACT
ESTs expressed sequence tags HIMF hypoxia-induced mitogenic factor ICAM-1 intercellular adhesion molecule 1 Ig superfamily immunoglobulin gene superfamily LPS lipopolysaccharide MCP-1 monocyte chemoattractant protein 1 M-CSF macrophage colony stimulating factor MEKK1 mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1 MGSA/gro-α melanoma growth stimulating activity gro-α MLK3 mixed-lineage kinase 3 mTOR mammalian target of rapamycin NF-κB nuclear factor-κB NIK NF-κB-inducing kinase PDGF platelet-derived growth factor PI3K phosphoinositide 3-kinase PIP2 phosphatidyl-inositol (4,5)-biphosphate PIP3 phosphatidyl-inositol (3,4,5)-triphosphate PKR protein kinase R RANTES regulated on activation normal T-cell expression and secreted TAK1 TGF-β-activated kinase
TFs transcription factors TNF-α tumor necrosis factor α VACM-1 vascular adhesion molecule 1 VLA-4 very late activation antigen 4 Vps34 vacuolar protein-sorting defective 34
1. Th e PI3K/Akt-NF-κB signaling pathways are ubiquitously expressed, including infl ammatory cells and vascular endothelium.
