ABSTRACT

Parathyroid carcinoma (PC) is a rare malignancy and also a rare cause of primary hyperparathyroidism. Diagnosis is usually suspected preoperatively on the basis of clinical, biochemical and radiological features. A palpable tumor in the neck or complaints of voice change with signs and symptoms of severe hypercalcemia; obvious end organ damage should raise suspicion of PC. Intraoperatively, firm-to-hard parathyroid mass with the loss of plane between mass and thyroid lobe or associated cervical lymphadenopathy may lead to clinical suspicion. Complete resection of the parathyroid tumor mass with ipsilateral thyroid lobe en bloc is the treatment of choice.