ABSTRACT
Liposomes are formed by concentric lamellas, and differ in composition, charge, size, and lamellarity. Classic liposomes are composed mainly of phospholipids and cholesterol, but nonconventional vesicles can carry also aptamers (proteins, antibodies), magnetic compounds, PEGylated lipids or other surfactant molecules in the lipid bilayer, aiming to achieve long time circulation and targeting, for drug delivery. This chapter describes the state-of-the-art liposomal formulations tested in clinical trials or that reached the market, classified accordingly to the carried drug: for the treatment of pain (including local anesthetics, opioids, and anti-inflammatories), infections (antibiotics and antifungals) and cancer.
