ABSTRACT
Most biological materials contain high water content. Removal of water through drying provides numerous benefits, including ease of handling and storage, reduction in transportation costs, and improved stability, to name a few. Though all drying techniques share a common objective, conceptually they are different and require modification/adaptation based on the properties of the compound. The spray drying process is conceptually simple; a solution is fed through an atomizer to create a spray, which is exposed to a suitable gas stream to promote rapid evaporation. When sufficient liquid mass has evaporated, the remaining solid material in the droplet forms an individual dried particle, which is then separated from the gas stream. Atomization produces a spray of droplets possessing a high surface-to-mass ratio that results from an energy source acting on liquid bulk. Minimum energy required for atomization is that needed to create a new air–liquid surface.
