ABSTRACT

Extracts of Punica granatum, Peganum harmala, Dianthus caryophyllus, and Vitis vinifera are known for their protective-antioxidative effects in various disorders. We examined the extracts ability to scavenge reactive oxygen species such as hydroxyl radicals, alkoxy-, and peroxy-type radicals by means of rotational 136viscometry. Determination of IC50 values and the capability of the extracts to reduce ABTS•+ and DPPH radicals were assessed by the ABTS and DPPH methods. Spectrophotometrically, we determined the content of tannins in the extracts. Results from rotational viscometry show that all examined extracts dose-dependently attenuated free-radical degradation of high-molar-mass hyaluronan. Punica granatum extract was the most effective in the ABTS and DPPH assays.