ABSTRACT
Curcumin, a natural polyphenol, shows some clinical activities. Poor solubility and less bioavailability, encapsulation method, nanonizations, micelle formation, and so on of hydrophobic drug, curcumin, is found to be very effective to increase the solubility of curcumin also increased its bioavailability. Water soluble polymer biomaterials combined with curcumin in form of mpeg-micelles, silver hydrogels, MMT formulation, polymer block have increased the thermal stability, solubility, and loading capacity of drug and efficiency of drug release encapsulation. They can be used as nano-carriers for hydrophobic drug in target drug delivery. These nanocarriers also increase the stability on surface as well as interior of nanoparticles. Release rate of drug is determined by the properties of polymer matrix of nanocarriers.
