ABSTRACT
A recent calculation by Grunwald estimated the total number of fascial nerve endings in an average human body at 100 million. This estimation related to the total mass of dense fibrous connective tissues, which based on the standard data set of Tanaka et al. There are several indications that the distribution of intrafascial nerve endings is not uniform throughout the body. Fascia contains different types of nerve endings. The vast majority can be characterized as sensory nerve endings. Among these, the free nerve endings are the most numerous. Fascia is also innervated by mechanosensory neurons with thick myelin sheets. They are assumed to serve proprioceptive functions. Free nerve endings in fascial tissues are sometimes associated with an interoceptive function. Their stimulation then provides the brain with information about the condition of the body in its constant search for physiological homeostasis.
