ABSTRACT
Emerging evidence on the presence of hormone receptors on fascia suggests that fascial alterations are subject to hormonal changes. This chapter will delve into the literature that reviews the impact of hormonal flux on fascia in the aging female body. These hormones include estrogen, progesterone, androgens [testosterone and dehydroepiandrosterone (DHEA)], and relaxin. It is necessary to understand the relationship between hormones and fascia and the potential clinical applications it may propose, especially in regard to declining hormone levels in the perimenopausal transition. Clinical manifestations of pain as well as other conditions including pelvic floor dysfunctions (pelvic organ prolapse and stress urinary incontinence) and gastroesophageal reflux disease may arise from alterations in the biomechanical properties of fascia due to hormones. This chapter will provide a progressive perspective on the importance of hormonal balance in assuring structural fascial integrity that contributes to healthy aging in women.
